Product Name :
3,3-Dimethyl-1-butanol (CAS 624-95-3)
Synonym :
Application :
CAS:
624-95-3
Purity:
Molecular Weight:
102.17
Formula :
C6H14O
Physical state:
Liquid
solubility :
Shipping Condition :
Store at room temperature
Melting point:
-60° C (lit.)
SMILES:
CC(C)(C)CCO
References:
:Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis. | Wang, Z., et al. 2015. Cell. 163: 1585-95. PMID: 26687352Gut Microbiota in Vascular Disease: Therapeutic Target? | Anbazhagan, AN., et al. 2017. Curr Vasc Pharmacol. 15: 291-295. PMID: 28056754Trimethylamine N-oxide (TMAO) as a New Potential Therapeutic Target for Insulin Resistance and Cancer. | Oellgaard, J., et al. 2017. Curr Pharm Des. 23: 3699-3712. PMID: 286415323,3-Dimethyl-1-butanol attenuates cardiac remodeling in pressure-overload-induced heart failure mice.133464-46-7 Molecular Weight | Wang, G., et al. 2020. J Nutr Biochem. 78: 108341. PMID: 32004931The gut microbial metabolite trimethylamine N-oxide aggravates GVHD by inducing M1 macrophage polarization in mice. | Wu, K., et al. 2020. Blood. 136: 501-515. PMID: 32291445Trimethylamine N-oxide impairs perfusion recovery after hindlimb ischemia. | Chen, L., et al. 2020. Biochem Biophys Res Commun. 530: 95-99. PMID: 32828321Repeated 3,3-Dimethyl-1-butanol exposure alters social dominance in adult mice. | Mao, J., et al. 2021. Neurosci Lett. 758: 136006. PMID: 34098029Trimethylamine N-oxide induces osteogenic responses in human aortic valve interstitial cells in vitro and aggravates aortic valve lesions in mice. | Li, J., et al. 2022. Cardiovasc Res. 118: 2018-2030. PMID: 34352088Maternal 3,3-Dimethyl-1-Butanol Therapy Protects Adult Male Rat Offspring against Hypertension Programmed by Perinatal TCDD Exposure. | Hsu, CN., et al. 2021. Nutrients. 13: PMID: 34578924Gut Microbial Metabolite Trimethylamine N-Oxide Aggravates Pulmonary Hypertension.159610-89-6 Computational Chemistry Data | Huang, Y.PMID:33402604 , et al. 2022. Am J Respir Cell Mol Biol. 66: 452-460. PMID: 35100519Inhibition of Trimethylamine N-Oxide Attenuates Neointimal Formation Through Reduction of Inflammasome and Oxidative Stress in a Mouse Model of Carotid Artery Ligation. | Chen, CY., et al. 2023. Antioxid Redox Signal. 38: 215-233. PMID: 35713239Initiation of 3,3-dimethyl-1-butanol at midlife prevents endothelial dysfunction and attenuates in vivo aortic stiffening with ageing in mice. | Casso, AG., et al. 2022. J Physiol. 600: 4633-4651. PMID: 36111692Gut Microbiota and Coronary Artery Disease: Current Therapeutic Perspectives. | Katsimichas, T., et al. 2023. Metabolites. 13: PMID: 36837875Carbamylation and decarbamylation of acetylcholinesterase: effect of choline, 3,3-dimethyl-1-butanol and some allosteric effectors. | Dawson, RM. 1978. J Neurochem. 30: 865-70. PMID: 565804Silicon-substituted medicinal agents. Parasympatholytic activity of 3,3-dimethyl-1-butanol carbamate and 2-trimethylsilyl-1-ethanol carbamate. | Fessenden, RJ. and Rittenhouse, R. 1968. J Med Chem. 11: 1070-1. PMID: 5697075