Product Name :
2-Deoxy-2-fluoro-D-galactose (CAS 51146-53-3)
Synonym :
Application :
CAS:
51146-53-3
Purity:
Molecular Weight:
182.15
Formula :
C6H11FO5
Physical state:
Solid
solubility :
Soluble in Ethanol, Methanol and Water
Shipping Condition :
Store at -20° C
Melting point:
131° C
SMILES:
OCC1OC(O)C(F)C(O)C1O
References:
:Synthesis of deoxyfluoro sugars from carbohydrate precursors. | Dax, K., et al. 2000. Carbohydr Res. 327: 47-86. PMID: 10968676Enzymatic synthesis of UDP-(3-deoxy-3-fluoro)-D-galactose and UDP-(2-deoxy-2-fluoro)-D-galactose and substrate activity with UDP-galactopyranose mutase. | Barlow, JN. and Blanchard, JS. 2000. Carbohydr Res. 328: 473-80. PMID: 11093703Differential mechanism-based labeling and unequivocal activity assignment of the two active sites of intestinal lactase/phlorizin hydrolase. | Arribas, JC., et al. 2000. Eur J Biochem. 267: 6996-7005. PMID: 11106409Inhibition of protein N-glycosylation by 2-deoxy-2-fluoro-D-galactose. | Gross, V., et al. 1992. Biochem J. 285 (Pt 3): 821-6. PMID: 14976192-Deoxy-2-fluoro-D-galactose protein N-glycosylation. | Loch, N., et al. 1991. FEBS Lett. 294: 217-20. PMID: 1756864Novel method for chase analysis of oligosaccharide metabolic error caused by xenobiotics. | Kato, T., et al. 2010. Anal Biochem. 405: 103-8. PMID: 20570645Metabolism and actions of 2-deoxy-2-fluoro-D-galactose in vivo.Pd-PEPPSI-IHept-Cl Order | Grün, BR.Fmoc-Phe(4-F)-OH In stock , et al.PMID:33738689 1990. Eur J Biochem. 190: 11-9. PMID: 2114284In vivo metabolism and UTP-depleting action of 2-deoxy-2-fluoro-D-galactose. | Grün, BR., et al. 1990. Adv Enzyme Regul. 30: 231-42. PMID: 2403033Structural basis for binding of fluorinated glucose and galactose to Trametes multicolor pyranose 2-oxidase variants with improved galactose conversion. | Tan, TC., et al. 2014. PLoS One. 9: e86736. PMID: 24466218Mechanism-based inhibitors of glycosidases: design and applications. | Kallemeijn, WW., et al. 2014. Adv Carbohydr Chem Biochem. 71: 297-338. PMID: 25480507Multi-level glyco-engineering techniques to generate IgG with defined Fc-glycans. | Dekkers, G., et al. 2016. Sci Rep. 6: 36964. PMID: 27872474Conserved Fc gamma R- glycan discriminates between fucosylated and afucosylated IgG in humans and mice. | Dekkers, G., et al. 2018. Mol Immunol. 94: 54-60. PMID: 29268168Synthetic strategies for fluorination of carbohydrates. | Uhrig, ML., et al. 2019. Org Biomol Chem. 17: 5173-5189. PMID: 31017598A 19F NMR study of 2-deoxy-2-fluoro-D-galactose in mice. | Kanazawa, Y., et al. 1988. Chem Pharm Bull (Tokyo). 36: 4213-6. PMID: 3245998The use of deoxyfluoro-D-galactopyranoses in a study of yeast galactokinase specificity. | Thomas, P., et al. 1974. Biochem J. 139: 661-4. PMID: 4369372