Product Name :
iFluor™ 488 Conjugated p75 NGF Receptor Recombinant Rabbit Monoclonal Antibody [SA39-02]
Predicted band size :
Observed band size :
Synonyms:
CD271 antibody CD271 antigen antibody Gp80 LNGFR antibody Gp80-LNGFR antibody Low affinity nerve growth factor receptor antibody Low affinity neurotrophin receptor p75NTR antibody Low-affinity nerve growth factor receptor antibody Nerve growth factor receptor antibody Nerve growth factor receptor TNFR superfamily member 16 antibody NGF receptor antibody 展开
Function :
The p75 neurotrophin receptor (p75NTR) was first identified in 1973 as the low-affinity nerve growth factor receptor (LNGFR) before discovery that p75NTR bound other neurotrophins equally well as nerve growth factor. p75NTR is a neurotrophic factor receptor. Neurotrophic factor receptors bind Neurotrophins including Nerve growth factor, Neurotrophin-3, Brain-derived neurotrophic factor, and Neurotrophin-4. All neurotrophins bind to p75NTR. This also includes the immature pro-neurotrophin forms. Neurotrophic factor receptors, including p75NTR, are responsible for ensuring a proper density to target ratio of developing neurons, refining broader maps in development into precise connections. p75NTR is involved in pathways that promote neuronal survival and neuronal death.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human p75 NGF Receptor aa 345-394 / 427.
Species reactivity:
Human, Mouse, Rat
Verify application:
IF-Cell
Coupling :
iFluor™ 488
Clone number:
SA39-02
RRID:
AB_3096804
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.1256825-86-1 In stock Aliquot store at -20℃.5-Methoxyoxindole Order Avoid repeated freeze / thaw cycles.PMID:33566787
Storage buffer solution:
Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 45 kDa
Positive control :
PC-12.