Product Name :
hNaa50p Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
MAK3 antibody FLJ13194 antibody hNAT5 antibody hSAN antibody Mak3 homolog (S. cerevisiae) antibody Mak3 homolog antibody N-acetyltransferase 13 (GCN5-related) antibody N-acetyltransferase 13 antibody N-acetyltransferase 5 antibody N-acetyltransferase san homolog antibody 展开
Function :
N-alpha-acetyltransferase that acetylates the N-terminus of proteins that retain their initiating methionine . Has a broad substrate specificity: able to acetylate the initiator methionine of most peptides, except for those with a proline in second position . Also displays N-epsilon-acetyltransferase activity by mediating acetylation of the side chain of specific lysines on proteins . Autoacetylates in vivo . The relevance of N-epsilon-acetyltransferase activity is however unclear: able to acetylate H4 in vitro, but this result has not been confirmed in vivo . Component of a N-alpha-acetyltransferase complex containing NAA10 and NAA15, but NAA50 does not influence the acetyltransferase activity of NAA10: this multiprotein complex probably constitutes the major contributor for N-terminal acetylation at the ribosome exit tunnel, with NAA10 acetylating all amino termini that are devoid of methionine and NAA50 acetylating other peptides . Required for sister chromatid cohesion during mitosis by promoting binding of CDCA5/sororin to cohesin: may act by counteracting the function of NAA10 .162405-09-6 Chemscene
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within human hNaa50p aa 1-50.BuyFmoc-His(3-Me)-OH
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3069543
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33550531 Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 19/9 kDa
Positive control :
A431 cell lysate, Hela cell lysate, mouse stomach tissue lysate, rat cerebellum tissue lysate, rat brain tissue, human thyroid tissue, rat cerebellum tissue, human skin tissue, human breast carcinoma tissue, Daudi.