Product Name :
Topoisomerase II alpha Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
alpha isozyme antibody ATP hydrolyzing DNA topoisomerase II alfa antibody DNA gyrase antibody DNA topoisomerase (ATP hydrolyzing) antibody DNA topoisomerase 2 alpha antibody DNA topoisomerase 2-alpha antibody DNA topoisomerase II 170 kD antibody DNA topoisomerase II alpha isozyme antibody DNA topoisomerase II antibody DNA Topoisomerase2 antibody 展开
Function :
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication.1402664-68-9 Data Sheet It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. It is essential during mitosis and meiosis for proper segregation of daughter chromosomes.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within C-terminal residues of Topoisomerase II alpha.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IHC-P, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3069575
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Hoveyda-Grubbs 2nd uses Aliquot store at -20℃ or -80℃.PMID:33539714 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 174 kDa
Positive control :
Jurkat cell lysate, NIH/3T3 cell lysate, A431 cell lysate, L929 cell lysate, A549 cell lysate, Human liver tissue lysate, HUVEC cell lysate, A549, Hela, A431, NIH/3T3, human tonsil tissue, human colon cancer tissue, human colon cancer tissue, Hela.