Product Name :
RON Recombinant Rabbit Monoclonal Antibody [SD2006]
Predicted band size :
152 kDa
Observed band size :
152 kDa
Synonyms:
c met related tyrosine kinase antibody CD136 antibody CD136 antigen antibody CDw136 antibody Macrophage stimulating 1 receptor (c met related tyrosine kinase) antibody Macrophage stimulating 1 receptor antibody Macrophage stimulating protein receptor alpha chain antibody MACROPHAGE STIMULATING PROTEIN RECEPTOR antibody Macrophage stimulating protein receptor beta chain antibody Macrophage-Stimulating 1 Receptor (MST1R) antibody 展开
Function :
Receptor protein tyrosine kinases (PTKs) have been classified into different subclasses on the basis of sequence similarity and distinct structural characteristics. The c-Met encoded receptor represents the initial member of one class of receptors characterized by a heterodimeric structure and a cysteine-rich extracellular domain. Ron, also designated macrophage-stimulating protein receptor (MSP receptor), p185-Ron, CD136 antigen or PTK8 represents a second member of this receptor class. The intracellular PTK domains of Ron and Met are highly similar (63% sequence identity) while the extracellular domains are less related (25% sequence identity) and both are rich in cysteine residues.Formula of 820231-27-4 Mature Ron receptor is comprised of a disulfide-linked heterodimer formed from an alpha chain (Ron α) and a beta chain (Ron β).Chlorin e6 Chemscene Proteolytic processing results in the separation of the N-terminal Ron α and C-terminal Ron β subunits.PMID:33475021
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human RON aa 11-60 / 1,400.
Species reactivity:
Human
Verify application:
WB, IF-Cell, IF-Tissue, IHC-P, FC, IP
Coupling :
unconjugated
Clone number:
SD2006
RRID:
AB_3070157
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 152 kDa
Positive control :
AGS cell lysates, A549, AGS, A431, human lung carcinoma tissue, human breast carcinoma tissue, THP-1.