Product Name :
Phospho-MCM2 (S108) Recombinant Rabbit Monoclonal Antibody [JE63-52]
Predicted band size :
102 kDa
Observed band size :
105 kDa
Synonyms:
BM28 antibody CCNL 1 antibody CCNL1 antibody CDC like 1 antibody cdc19 antibody CDCL 1 antibody CDCL1 antibody Cell devision cycle like 1 antibody Cyclin like 1 antibody D3S3194 antibody 展开
Function :
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within corresponding to residues surrounding ser108 of Human MCM2.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
JE63-52
RRID:
AB_3072145
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Buy5-Bromo-6-chloro-pyridine-2-carbaldehyde Aliquot store at -20℃.425380-38-7 supplier Avoid repeated freeze / thaw cycles.PMID:33509045
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 102 kDa
Positive control :
SiHa cell lysates, HL-60 cell lysates, rat large intestine tissue, human lymph node tissue, human small intestine tissue, mouse testis tissue.