Product Name :
PSMD12 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
26S proteasome non-ATPase regulatory subunit 12 antibody 26S proteasome regulatory subunit p55 antibody 26S proteasome regulatory subunit RPN5 antibody MGC75406 antibody p55 antibody proteasome (prosome macropain) 26S subunit non ATPase12 antibody Proteasome 26S non ATPase subunit 12 isoform 2 antibody PSD12_HUMAN antibody 展开
Function :
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.Sodium difluoromethanesulfinate Data Sheet This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. Alternatively spliced transcript variants encoding
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
The antiserum was produced against synthesized peptide derived from human PSMD12.1272758-17-4 Chemical name AA range:151-200
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33543866 Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
50 kDa
Positive control :
Brain,Muscle,Platelet,Testis,Tongue,