Product Name :
PRDM5 Mouse Monoclonal Antibody [12C-D4]
Predicted band size :
Observed band size :
Synonyms:
BCS2 antibody PFM 2 antibody PFM2 antibody PR domain containing 5 antibody PR domain containing protein 5 antibody PR domain zinc finger protein 5 antibody PR domain-containing protein 5 antibody PRDM 5 antibody PRDM5 antibody PRDM5 protein antibody 展开
Function :
A cDNA of PRDM5 was isolated based upon its homology to the PR domain of PRDM2. The gene encodes an open reading frame of 630 amino acids and contains a PR domain in the NH-terminal region followed by 16 zinc finger motifs. Through radiation hybrid analysis, PRDM5 was mapped to human chromosome 4q27, a region thought to contain tumor suppressor genes for ovarian, breast, lung, liver, colon, and other cancers. The gene has a CpG island promoter and is silenced in human breast, ovarian, and liver cancers. Upon infection of tumor cells, a recombinant adenovirus expressing PRDM5 causes G2/M arrest and apoptosis, suggesting that inhibition of PRDM5 may be involved in carcinogenesis.
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Recombinant protein
Species reactivity:
Human, Mouse
Verify application:
WB, ICC, FC
Coupling :
unconjugated
Clone number:
12C-D4
RRID:
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
4℃; -20℃ for long term storage.Formula of Bis(3-aminopropyl) ether
Storage buffer solution:
Purified antibody in PBS with 0.8-Bromo-3-chloroisoquinoline manufacturer 05% sodium azide.PMID:33459922
Subtype:
IgG1
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
73 kDa
Positive control :
Human PRDM5 recombinant protein, PRDM5-hIgGFc transfected HEK293 cell lysate, Hela, MCF-7.