Product Name :
PLA2G12A Mouse Monoclonal Antibody [C11-H2]
Predicted band size :
Observed band size :
Synonyms:
EC 3.1.1.4 antibody Group XII secreted phospholipase A2 antibody Group XIIA secreted phospholipase A2 antibody Group XIIA secretory phospholipase A2 antibody Group XIIA secretory phospholipase A2 precursor antibody GXII antibody GXII sPLA2 antibody PG12A_HUMAN antibody phosphatidylcholine 2 acylhydrolase 12A antibody Phosphatidylcholine 2 acylhydrolase GXII antibody 展开
Function :
Secreted phospholipases A2 (sPLA2s) form a large family of structurally related enzymes, which are widespread in nature. Snake venoms have been known for decades to contain a tremendous molecular diversity of sPLA2s, which can exert a myriad of toxic and pharmacological effects. Secreted phospholipase A2 enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as group XIIA sPLA2, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s. Group XIIA sPLA2, also known as GXII, ROSSY, PLA2G12 or PLA2G12A, is a 189 amino acid secreted protein that localizes to the cytoplasm. Belonging to the phospholipase A2 family, group XIIA sPLA2 is abundantly expressed in heart, skeletal muscle, kidney, liver and pancreas
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Recombinant protein
Species reactivity:
Human
Verify application:
WB, IHC-P, FC
Coupling :
unconjugated
Clone number:
C11-H2
RRID:
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
4℃; -20℃ for long term storage.2,6-Dibromopyridin-4-amine web
Storage buffer solution:
Purified antibody in PBS with 0.Dabigatran web 05% sodium azide.PMID:33445186
Subtype:
IgG1
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
21 kDa
Positive control :
Human PLA2G12A recombinant protein, PLA2G12A-hIgGFc transfected HEK293 cell lysate, human liver tissue, Hela.